🧠 CerebrumDAO Contributor Newsletter May/June 2025
As we close out the first half of the year, Cerebrum DAO continues to gain momentum across research, community, and infrastructure. From growing our pipeline of promising neurodegenerative therapeutics to expanding community engagement and launching key products, this month marked significant progress on multiple fronts. Here's a snapshot of where we stand and where we’re heading.
🔑 Key Metrics
Treasury: $5.32M total value | Total Capital Deployed: $1.4m
45+ Total projects sourced | 7 Projects funded | 4 IP-NFTs minted | 6 IP-NFTs in the pipeline
Discord Members 1970 (+50) | Active 108 | X Followers: 5408 (+200) | Substack Subs: 120 (+13)
Telegram community server launched: https://t.me/cerebrumdao
Meet the Scientists with Fission Bio
Portfolio Updates
Percepta:
Ethics board study application finalized and submitted.
Began sourcing pTau-217 as a blood biomarker for the trial.
Trial approval expected: June/July 2025.
Fission Bio:
Built selection assay for screening.
Currently testing 90 selected, cost-effective compounds.
First results expected in a few weeks.
SK Channels / Ataxia:
Partnership with Sygnature Discoveries (UK) launched.
Testing 35 compounds: includes known and 19 new variants for improved Structure Activity Relationship (SAR) and KCa2.2 selectivity.
Transfidelity
Successful kickoff on June 9th in Basel.
Results expected August (onsite/Zoom meeting).
NEURON-SK and IP-NFTs
NEURON-SK minted and added to the IP-NFT portfolio.
Targets SK-Channels to treat SCA & ET with novel molecule class.
Molecule Labs launched data rooms for:
Sourcing Updates
🔍 Deal Sourcing Areas
✔️ Blood-borne biomarkers of neurodegeneration
✔️ Pluripotent Mesenchymal Stem Cells for brain aging/neurodegeneration
✔️ Drug delivery innovations for Huntington's Disease (MusiQ Bio)
✔️ Role of dark microglia, lipid accumulation, and neuroinflammation in Alzheimer’s
🧬 Research Partnerships & Sourcing
Engaged with:
Ben Readhead (common pathogens & Alzheimer's)
Carrigent (delivery platform for DNA/RNA/proteins)
Max Planck Institute (DeSci initiative) – IP storage via blockchain
MusiQ Bio – non-invasive, ultrasound-triggered drug delivery for Huntington’s Disease
🛠️ Product Working Group (Product WG)
📌 Partnerships
Initiated discussions with AxonDAO for integration into the product ecosystem and a development partnership.
🚀 Product Development
NEURON Wallet app: Design phase initiated.
Marketplace: Development kicked off; targeted Q3 release.
Supplement Stack: Development initiated for the marketplace.
🌱 Community Growth Working Group
🔊 Events & Campaigns
DeSci Berlin: Huge success (largest DeSci event to date).
DeSci Solana: Celebrated participation and support from Solana community.
Swiss Biotech Day: Panel discussion, biotech community engagement.
Welshare Health workshop: Collaboration push on productivity tools.
Supported Alzheimer’s Awareness Month with Alzheimer’s Association:
https://x.com/alzassociation #ENDALZ
📢 Media & Content
Axon DAO x Cerebrum DAO Podcast (Mark featured):
https://x.com/AxonDAO/status/1933252968092238240Meet the Scientist feature on mito-protective agents:
https://x.com/Cerebrum_DAO/status/1930294567137620013NEURON on Solana (NEURON/BIO):
https://x.com/Cerebrum_DAO/status/1930332509063270524
Radium swap link: https://raydium.io/swap/?inputMint=bioJ9JTqW62MLz7UKHU69gtKhPpGi1BQhccj2kmSvUJ&outputMint=neuRodi6Saw2cwDpud7FyAcjzqPBJDtr3fDTXE2Fu4
🧬 Looking Ahead
From the lab bench to the blockchain, Cerebrum DAO is building a more decentralized, collaborative, and effective future for brain health research. With major trial milestones on the horizon, a growing IP-NFT portfolio, and new partnerships forming every week, the second half of 2025 is shaping up to be transformative.
Thank you for being part of this journey. Stay connected, stay curious and as always, reach out if you want to build with us.
Join the conversation: Telegram Server
Follow our progress: X | Substack